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| BRAZILIAN PEPPERTREE |
Family: Anacardiaceae
Genus: Schinus
Species: molle
Common Names: Brazilian
Peppertree, Aroeira, Escobilla, Peruvian Peppertree, Peruvian Mastic Tree,
California Peppertree, Mastic-Tree, Aroeira Salsa, Aguaribay, American Pepper,
Anacahuita, Castilla, False Pepper, Gualeguay, Jesuit's Balsam, Molle Del Peru,
Mulli, Pepper Tree, Pimentero, Pimientillo, Pirul |
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| DESCRIPTION |
Properties/Actions: |
Analgesic, Antibacterial, Antidepressant, Antimicrobial, Antifungal,
Antiviral, Antispasmodic, Astringent, Balsamic, Cytotoxic, Diuretic,
Expectorant, Hypotensive, Purgative, Stomachic, Tonic, Uterine Stimulant,
Vulnerary |
Phytochemicals: |
a-Amyrin, Behenic Acid, A-Bergamont-trans-ene, Bourbonene, d-Cadinene,
a-Cadinol, d-Cadinol, t-Cadinol, a-Calacorene, g-Calacorene,
iso-Calamenediol, Calamenene, Calcium, Camphene, Car-3-ene, Carvacrol,
b-Caryophyllene, Cerotic Acid, a-Copaene, Croweacin, a-Cubebene,
para-Cymene, b-Elemene, Elemol, b-Elemonic acid, a-Eudesmol, b-Eudesmol,
g-Eudesmol, Fisetin, Gallic Acid, Geraniol Butyrate, Germacrene D,
b-Guaiene, a-Gurjunene, Heptacosanoic acid, a-Humulene, Laccase,
Lignoceric acid, Limonene, (+)Limonene, Linoleic Acid, dihydro-Malvalic
acid, iso-Masticadienoic acid, 3-epi-Iso-Masticadienolalic acid,
iso-Masticadienolic acid, Menth-cis-2-en-1-ol, a-Muurolene, g-Muurolene,
t-Muurolol, Myrcene, Nerol hexanoate, Octacosanoic acid, Octanoic Acid
Methyl Ester, Oleic acid, Palmitic acid, Pentacosanoic acid,
Pentan-1-ol,3-methyl, Peroxidase, a-Phellandrene, b-Phellandrene,
ortho-ethyl Phenol, Pinene, a-Pinene, b-Pinene, Piperine, trans-Piperitol,
Protocatechuic acid, Quercetin, Quercetrin, Quercitrin, iso-Quercitrin,
Raffinose, Rutin, Sabinene, b-Sitosterol, b-Spathulene, Tannin,
a-Terpinene, g-Terpinene, a-Terpineol, Terpinolene, Tricosanoic acid,
Cyanidin-3-o-alpha-l-galactoside,
Peonidin-3-o-beta-d-glucoside |
Traditional Remedy: |
One-half cup dried bark or seed decoction 1-2 times daily or 1-2 ml of
a 4:1 tincture 1-2 times daily. 1-2 grams of powdered bark in tablets or
capsules daily can be substituted if desired. See Traditional Herbal Remedies
Preparation Methods page if necessary for definitions. |
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| ETHNOBOTANY: WORLDWIDE USES |
Argentina |
Diarrhea, Dysmenorrhea, Emmenagogue, Menstrual Disorders, Respiratory
Tract Infections, Urinary Tract Infections |
Brazil |
Astringent, Balsamic, Blenorrhagia, Bronchitis, Cough, Cystitis,
Urethritis, Diarrhea, Fever, Inflammation, Purgative, Respiratory Tract
Disorders, Stimulant, Tonic, Tumor, Urinary Tract
Disorders |
Columbia |
Diarrhea, hemoptysis, rheumatism |
Elsewhere |
Amenorrhea, Bronchitis, Diuretic, Dysmenorrhea, Edema, Emmenagogue,
Expectorant, Eye, Gingivitis, Hypertension, Gout, Piscicide, Poison,
Purgative, Rheumatism, Sore Schinus, Stomachic, Swelling, Urogenital,
Venereal, Viricide |
La |
Masticatory, Purgative, Spice, Tea |
Mexico |
Aposteme, Asthma, Astringent, Balsamic, Blennorrhagia, Bronchitis,
Cataract, Colic, Collyrium, Conjuntivitis, Cough, Digestive Disorders,
Foot, Gonorrhea, Gripe, Gum, Liqueur, Masticatory, Mouth, Ophthalmia,
Preventitive, Purgative, Rheumatism, Sore, Stomachache, Toothache,
Tuberculosis, Tumor, Ulcer, Urogenital, Venereal, Vulnerary,
Wound |
Paraguay |
Blennorrhagia, Diuretic, Emmenagogue, Sore, Urethritis,
Wound |
Peru |
Antiseptic, Cicatrizant, Diuretic, Fractures, Purgative, Rheumatism,
Toothache, Tumor, Wart |
So. Africa |
Arrhythmia, Antidepressant, Colds, Gout, Hypertension,
Rheumatism |
Turkey |
Diuretic, Expectorant, Gonorrhea, Masticatory, Purgative, Stomachic,
Tonic |
Uruguay |
Amenorrhea, Dysmenorrhea |
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Brazilian Peppertree is a medium to small shrubby tree growing 4-8
meters in height with a trunk 25-35 cm in diameter and narrow spiky leaves. It
produces an abundance small flowers formed in panicles, then bears a great
many small flesh-colored berry-like fruits in December and January. It is
indigenous to South and Central America and can be found in semi-tropical and
tropical parts of the United States. |
Virtually all parts of this tropical tree has been used medicinally
throughout the tropics including its leaves, bark, fruit, seeds, resin and
oleoresin or balsam. It has an ancient history of use and the plant shows up
in ancient religious artifacts or idols among some of the Chilean
Amerindians.(1) All parts of the tree have a high oil and essential
oil content which produces a spicy aromatic scent. The leaves of Brazilian
Peppertree have such a high oil content that leaf pieces jerk and twist when
placed in hot water as the oil is released. The berries have a peppery flavor
and have been used in syrups, vinegar and beverages in Peru, in Chilean wines,
and are dried and ground up for a pepper substitute in Africa.(1) The dried fruits have even been used as an adulterant of black pepper in some
countries. The tree also produces an resin and oleoresin or balsam which is
used medicinally. |
Brazilian Peppertree has a long history of uses throughout South and
Central America and is reported to be astringent, balsamic, collyrium,
diuretic, emmenagogue, masticatory, piscicide, purgative, stomachic, tonic,
antiviral and vulnerary.(1) Its uses by indigenous peoples in the
countries where it grows are well documented. In Peru the sap is used as a
purgative and diuretic,(2) and the entire plant is used externally
for fractures and as a topical antiseptic.(3) The oleoresin in Peru
is used externally as a cicatrizant and for toothaches and taken internally
for rheumatism, a folk disease called "Suto," and as a
purgative.(4) In South Africa, a leaf tea is used to treat colds,
and a leaf decoction is inhaled for colds, hypertension, depression, and
arrhythmia.(5) In the Brazilian Amazon, a bark tea is used as a
purgative(6) and a bark and leaf tea is used as a stimulant and
antidepressant.(7) In Argentina, a decoction is made with the dried
leaves and is taken for menstrual disorders,(8) as well as
respiratory and urinary tract infections and disorders.(9) |
Brazilian Peppertree is still employed in herbal medicine today in many
countries. It is used for many conditions in the tropics including,
amenorrhea, apostemes, blenorrhagia, bronchitis, cataracts, dysmenorrhea,
gingivitis, gonorrhea, gout, ophthalmia, rheumatism, sores, swellings,
tuberculosis, ulcers, urethritis, urogenital and venereal disorders, warts and
wounds.(1, 10-12) In Brazilian herbal medicine today, the dried
bark or leaves are employed for fevers, urinary tract disorders and pain,
cystitis, urethritis, blenorrhagia, coughs, bronchitis, and other upper
respiratory problems, gripe, diarrhea, hemorrhages and menstrual disorders
with excessive bleeding, tumors, and general inflammation.(13, 14) |
Phytochemical analysis of Brazilian Peppertree reveals that the plant
contain tannins, alkaloids, flavonoids, steroidal saponins, sterols, terpenes,
gums, resins, and essential oils.(15-17) The essential oil, present
in the leaves, bark and fruit, are a rich source of triterpenes,
sesquiterpenes and monoterpenes and many of the plant's documented biological
activities are attributed to the essential oils found in the plant. The fruit
can contain up to 5% essential oil and the leaves can contain up to 2%
essential oil.(12, 15, 16) In laboratory tests, the essential oil
as well as a leaf extract demonstrated good to very strong antifungal actions
against numerous fungi and even candida in vitro.(18-20) The
essential oil and leaves have clinically demonstrated in vitro antibacterial
and antimicrobial activity against numerous bacteria and pathogens in several
studies.(19-21) In much earlier in vitro tests, a leaf extract of
Brazilian Peppertree demonstrated antiviral actions against several plant
viruses(22) and was shown to be cytotoxic against 9kb cancer
cells.(23) |
Several research groups have conducted animal studies over the years on
Brazilian Peppertree which has substantiated some of its many traditional uses
in herbal medicine. A fruit extract and a leaf extract were shown to produce
an hypotensive activity in dogs and rats,(24, 25) as well as
uterine stimulant activity in guinea pigs and rabbits.(25, 26) Most
recently, leaf extracts tested by other researchers between 1996 and 1997
demonstrated analgesic activity in mice(27) and antispasmodic
properties in rats.(28) The essential oil was also shown to be an
effective insect repellant against the common housefly in 1996.(29) |
Today, herbalists and natural health practitioners in both North and South
America use Brazilian Peppertree mostly for viral and bacterial infections
like colds, flu, asthma, bronchitis and other upper respiratory infections, as
an aid to help lower high blood pressure, and as a female balancing herb for
numerous menstrual disorders, menstrual cramps, PMS and
menopause.
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Foot notes: |
- Duke, JA, 1985. Handbook of Medicinal Herbs 1985. Ed. CRC
Press: Boca Raton, FL
- Kramer, F. L. 1957. The Pepper Tree Schinus Molle. Econ Bot 11 : 322-326
(1957)
- Yelasco-Negueruela, A., 1995., Medicinal Plants from Pampallakta: an
Andean Community in Cuzco (Peru). Fitoterapia 66 5: 447-462 (1995)
- Ramirez, V. R. et.al., 1988. Vegetales Empleados En Medicina
Tradicional NorperuanaBanco Agrario Del Peru & Nacl Univ Trujillo,
Trujillo, Peru, June, 1988 : 54pp- (1988)
- Bhat, R. B. et.al., 1995. Traditional Herbal Medicine in Transkei. J
Ethnopharmacol 48 1: 7-12 (1995)
- Burkill,IH., 1966. Dictionary of the Economic Products of the Malay
Peninsula. Ministry of Agriculture and Cooperatives, Kuala Lumpur,
Malaysia. Volume II.
- Elisabetsky, E., et al., 1992. Traditional Amazonian Nerve Tonics as
Antidepressant Agents: Chaunochiton Kappleri: a Case Study. J Herbs
Spices Med Plants 1 1/2: 125-162 (1992)
- Gonzalez, F., et.al., 1987. A Survey of Plants with Antifertility
Properties Described in the South American Folk Medicine Abstr Princess
Congress I Bangkok Thailand 10-13 December 1987 : 20pp-. (1987)
- Perez, C., et.al., 1994. Inhibition of Pseudomonas Aerguinosa by
Argentinean Medicinal Plants. Fitoterapia 65 2: 169-172 (1994)
- Hartwell, J.L., 1971. Plant used againt canter. A survey. Lloydia, p.30, 1967-1971.
- Duke, JA, & Wain, KK 1981. Medicinal Plants of the World,
Computer index, 85,000 entries, 3 vols., 1981. 1654
- List, PH and Horhammer, L., 1979. Hager's Handbuch der
Pharmazeutischen Praxis, Vols. 2 to 6., Springer-Verlag, Berlin,
Germany 1969-1979.
- Cruz, G.L. 1995. Dicionario Das Plantas Uteis Do Brasil, 5th
ed., Bertrand: Rio de Janeiro, Brazil
- Coimbra, Raul, 1994. Manual de Fitoterapia 2nd Ed., Editora
Cejup: Belem, Brazil.
- Terhune, S., et.al., 1974. B-spathulene: a new sesquiterpene in Schinus
molle oil, Phytochemistry, 13, 865(1973)
- Dominguez, X., et.al., 1970. A Chemical Survey of Seventeen Medicinal
Mexican Plants. Planta Med 18 : 51- (1970)
- Pozzo-Balbi, T., et.al., 1978. The Triterpenoid Acids of Schinus molle. Phytochemistry17 : 2107-2110 (1978)
- Dikshit A, 1986 Schinus molle: a new source of natural fungitoxicant. Appl Environ Microbiol 51(5), 1085-1088 (1986)
- L-Keltawi, N. et.al., 1980. Antimicrobial Activity of Some Egyptian
Aromatic Plants.Herba Pol 26 4: 245-250 (1980)
- Gundidza, M., et.al., 1993. Antimicrobial Activity of Essential Oil from
Schinus molle Linn. Central Africian J Med 39 11: 231-234 (1993)
- Ross, S., et.al., 1980. Antimicrobial Activity of Some Egyptian Aromatic
Plants. Fitoterapia 51 : 201-205 (1980)
- Simons, J., et.al., 1963. Succulent-type as Sources of Plant Virus
Inhibitors. Phytopathology 53 : 677-683 (1963)
- Bhakuni, D., et.al., 1976 Screening of Chilean Plants for Anticancer
Activity. I. Lloydia39 4: 225-243 (1976)
- Bello, R. et.al., 1996. Effects on Arterial Blood Pressure of the
Methanol and Dichloromethanol Extracts from Schinus molle L. in Rats. Phytother Res 10 7: 634-635 (1996)
- Zaidi, S. et.al., 1970. Some Preliminary Studies of the Pharmacological
Activities of Schinus molle. Pak J Sci Ind Res 13 : 53- (1970)
- Moreno, M. 1922. Action of Several Popular Medicaments on the Isolated
Uterus. C R Seances Soc Biol Ses Fil 87 : 563-564 (1922)
- Barrachina, M., 1997. Analgesic and Central Depressor Effects of the
Dichloromethanol Extract from Schinus molle L. Phytother Res 11 4:
317-319 (1997)
- Bello, R., et.al, 1996. Effects on Arterial Blood Pressure of the
Methanol and Dichloromethanol Extracts from Schinus molle L. in Rats. Phytother Res 10 7: 634-635 (1996)
- Wimalaratne, P., et.al., 1996. Isolation and Identification of House
Fly, Musca domestica L., Repellents from Pepper Tree, Schinus molle L J
Chem Ecol 22 1: 49-59 (1996)
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Clinical Abstracts |
Antimicrobial activity of essential oil from Schinus molle
Linn.
Gundidza M
Department of Pharmacy, Faculty of Medicine,
University of Zimbabwe, Harare.
Cent Afr J Med 1993 Nov;39(11):231-234
The essential oil from the fresh leaves of Schinus molle isolated by
hydrodistillation was tested for antibacterial activity using the hole plate
diffusion method and for antifungal activity using the mycelium or single cell
growth inhibition method. Results obtained showed that the volatile oil
exhibited significant activity against the following bacterial species:
Klebsiella pneumoniae, Alcaligenes faecalis, Pseudomonas aeruginosa,
Leuconostoc cremoris, Enterobacter aerogenes, Proteus vulgaris, Clostridium
sporogenes, Acinetobacter calcoacetica, Escherichia coli, Beneckea natriegens,
Citrobacter freundii, Serratia marcescens, Bacillus subtilis and Brochothrix
thermosphacata. The fungal species Aspergillus ochraceus, Aspergillus
parasiticus, Fusarium culmorum and Alternaria alternata exhibited significant
sensitivity to the volatile oil.
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Schinus molle: a new source of natural fungitoxicant.
Dikshit
A, Naqvi AA, Husain A
Appl Environ Microbiol 1986 May;51(5):1085-1088
The oil of Schinus molle exhibited the maximum fungitoxic activity during
the screening of some essential oils against some common storage and animal
pathogenic fungi. It showed absolute toxicity against animal pathogens and
mild activity against storage fungi. The effective concentrations of the oil
varied from 200 to 900 ppm. The toxicity of the oil persisted up to 80 degrees
C and 90 days of storage but declined when autoclaved. It withstood heavy
inoculum density. The oil exhibited a narrow range of activity and was found
to be more effective than Multifungin, an antifungal drug. The oil was
characterized by its various physicochemical properties. It was found to
comprise 50 constituents. It appeared that some changes in the oil
constituents during storage affected its fungitoxic potency. |
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