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CARAPIA
Family: Moraceae
Genus: Dorstenia
Species: brasiliensis
Common names: Carapia, Carapá, Chupa-chupa, Conta-de-cobra, Bezoar, Bezoard, Contrajerva, Contra-erva, Contrayerba De Las Antillas, Contrayerva
Parts Used: Roots
 
DESCRIPTION
Properties/Actions:
Antacid, Analgesic, Antifatigue, Anti-inflammatory, Aromatic, Bitter, Diaphoretic, Digestic, Diuretic, Emmemogogue, Febrifuge, Purgative, Tonic, Stimulant, Stomachic, Tonic
Phytochemicals Include:
COUNTRY
ETHNOBOTANY: WORLDWIDE USES
Argentina
Diaphoretic, Diuretic, Emetic, Emmenagogueue, Fever, Tonic
Brazil
Anemia, Bite(Snake), Constipation, Cystitis, Diuretic, Diaphoretic, Diarrhea, Dysentery, Emetic, Emmenagogueue, Febrifuge, Gastritis, Purgative, Stimulant, Stomachic, Tonic, Uterine
Elsewhere
Alexipharmic, Cough, Diaphoretic, Gastritis, Stimulant

Clinical References

  • Iwu MM, 1992 Evaluation of plant extracts for antileishmanial activity using a mechanism-based radiorespirometric microtechnique (RAM). Planta Med 58(5), 436-441 (1992)
  • Ruppelt BM, 1991 Pharmacological screening of plants recommended by folk medicine as anti-snake venom--I. Analgesic and anti-inflammatory activities. Mem Inst Oswaldo Cruz 86, 203-205 (1991)

Clinical Abstracts

Pharmacological screening of plants recommended by folk medicine as anti-snake venom--I. Analgesic and anti-inflammatory activities.
Ruppelt BM, Pereira EF, Goncalves LC, Pereira NA
Departamento de Farmacologia, CCS-ICB, UFRJ, Ilha do Fundao, Rio de Janeiro, Brasil.
Mem Inst Oswaldo Cruz 1991;86 Suppl 2:203-205
We have observed that several plants used popularly as anti-snake venom show anti-inflammatory activity. From the list prepared by Rizzini, Mors and Pereira some species have been selected and tested for analgesic activity (number of contortions) and anti-inflammatory activity (Evans blue dye diffusion--1% solution) according to Whittle's technique (intraperitoneal administration of 0.1 N-acetic acid 0.1 ml/10 g) in mice. Previous oral administration of a 10% infusion (dry plant) or 20% (fresh plant) corresponding to 1 or 2 g/kg of Apuleia leiocarpa, Casearia sylvestris, Brunfelsia uniflora, Chiococca brachiata, Cynara scolymus, Dorstenia brasiliensis, Elephantopus scaber, Marsypianthes chamaedrys, Mikania glomerata and Trianosperma tayuya demonstrated analgesic and/or anti-inflammatory activities of varied intensity.

Evaluation of plant extracts for antileishmanial activity using a mechanism-based radiorespirometricmicrotechnique (RAM).
Iwu MM, Jackson JE, Tally JD, Klayman DL
Department of Medicinal Chemistry, Walter Reed Army Institute of Research, Washington, D.C. 20307.
Planta Med 1992 Oct;58(5):436-441
Extracts of eleven plants used in Nigerian traditional medicine have been evaluated for possible antileishmanial activity using a radiorespirometric microtest technique based on in vitro inhibition of catabolism of 14CO2 from a battery of 14C-substrates by promastigotes. Of 13 methanol extracts tested, 5 from Gongronema latifolia, Dorstenia multiradiata, Picralima nitida, Cola attiensis, and Desmodium gangeticum, were active at concentrations of 50 micrograms/ml or less against a visceral Leishmania isolate.
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